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P. 219

POSTER PRESENTATION / POSTER SUNUM



                                                         Postbiotics



                                                        İlker ŞİMŞEK
                                                                    *
                           Çankırı Karatekin University, Şabanözü Vocational School, Çankırı, TÜRKIYE



               Correspound Author: İlkers@karatekin.edu.tr



                     Postbiotics are beneficial metabolic byproducts released after cellular lysis, such as peptides,

               polysaccharides, teichoic acids, enzymes, organic acids, and  cell surface proteins, secreted  by
               probiotic bacteria.  Postbiotics  are generally produced by  certain  genera of the  Lactobacillaceae

               family and strains of the Bifidobacterium genus, as well as lactic acid bacteria such as Pediococcus,
               Streptococcus, and Lactobacillus.

                     Postbiotics have anti-inflammatory, antioxidant,  antihypertensive, antiproliferative,
               antimicrobial, hypocholesterolemic, and immunomodulatory effects, or they synthesize metabolites

               and products from microbial enzymatic activity on the food matrix.

                     Postbiotics exhibit multifaceted mechanisms in terms of  their health effects. Postbiotics
               possess various properties, including regulation of intestinal microbiota and epithelial barrier function
               through bacteriocin production;  modulation  of immune  cell responses through the production of

               metabolites such as peptidoglycan, lipoteichoic acid, and exopolysaccharide; and inhibitory effects
               against  pathogens through their antibiofilm  properties. Because postbiotics do not contain live
               microorganisms, the risks associated with their consumption are reduced.

                     The use of postbiotics in clinical practice is still a developing field. Compared to probiotics, they

               offer advantages such as longer shelf life, lower cost, and ease of standardization. Postbiotics have
               the potential to play a significant role in personalized nutrition and therapeutic approaches in the
               future.


               Keywords: Postbiotic, Probiotic, functional food.













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